What version of Painter were did you use Dave? I did my first pro digital inking with Painter and it worked really nicely for me. I use Photoshop now tho because I can do everything there. Manga Studio has a really nice set of tools and has something of a more natural feel to it, not to mention that auto smoothing is awesome. Can't get on with inking in Illustrator. Vectors are great for some forms of art, particularly a cartoony style, but I'm not keen on it for a more harder edged comic style.