I've one for Tales of Telguuth. Ramathor the Necromancer, right, is about to smite the thief Grinthal into the netherworlds of Ka'an, okay, when a big feck-off nuclear bomb lands on them, destroying not only the two lads but the whole Telguuth and the galactic bleeding hub as well, and they all never show their sorry faces in 2000AD again.